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December 14 , 2010

Genetic Breakdown

The Truth about Vioxx, Bextra, and Celebrex


We all get sick from time to time and have to go to the doctor. The doctor prescribes medication, we go home and take the medication with trust in their judgment that first we were diagnosed properly and secondly that the medication will work without causing serious bodily harm or even death. In 1999 a pharmaceutical company took on a common problem that affects one in three Americans; arthritis. There are over one hundred different types of arthritis but nevertheless it can be a very painful, debilitating disease and in some cases it can case death. Many were treating the problem with aspirin but they could not tolerate it because it caused gastrointestinal bleeding. After clinical trials the pharmaceutical company discovered that this new drug not only caused sudden cardiac arrest but it also caused a host of other medical problems. The manufacturer decided to market the drug anyway and thousands of Americans died or were injured but sadly enough many don’t know why. This book answers that question and many more. Many people suffer from arthritis which causes an inflammatory response and pain in the joints. There are three common types of arthritis; rheumatoid, osteoarthritis and infectious arthritis although there are over one hundred different known categories. There is no cure for arthritis. This disease attacks the joints and causes pain and stiffness. The difference between Osteo and Rheumatoid is that the latter will not only destroy the joints but it will also affect the vocal cords causing hoarseness. When the disease is finished running its course by systemically destroying the joints and surrounding muscle, it will destroy organs and tissue as well. Osteoarthritis is limited to joint destruction. It will break down cartilage primarily affecting the hands feet and spine. Most people suffering with infectious arthritis already have an existing joint problem that has exacerbated into infectious arthritis. You’ve heard the expression, no pain, no gain. You don’t have to have arthritis to reach for an aspirin. Just the pain from working out in the gym or a hard day at the job may require an aspirin. Usually it begins with minor joint pain that is treated with aspirin. When we have a minor ache or pain we take an aspirin. When we have a headache we take an aspirin. You can go anywhere in the world and this is one pharmaceutical that has gained worldwide recognition and deservedly so. The chemical name for Aspirin is acetylsalicylic acid and has been used for years as an analgesic which means it will relieve minor aches and pains. It will also reduce fever and inflammation. Aspirin has been the wonder drug and the answer to pain, fever and inflammation for years. As we already know, the human body is very complex. After we ingest anything it goes directly to the stomach which is considered a hollow organ. This organ contains gastric juices or enzymes which are prepared to digest and break down food, liquids or medicine so that the human body can receive a benefit. There are digestive enzymes present that break down whatever is in that stomach environment and changes it from large molecules into smaller ones so that they can move on into the smaller intestine. Once there, they can be absorbed by the human body. In order for this to be achieved, the stomach environment contains up to three liters of gastric juices. Gastric juice is a hormone that comes from gastrin. After it is broken down the molecules are called peptides or chemical bonds and then it is released directly into the bloodstream. Think of the body as a computer. It will detect that there are peptides in the stomach. However if the body detects that there are too many peptides then the human computer will continue to send gastric juice and will not turn off until it feels that everything has been broken down. The result is gastrointestinal bleeding. Aspirin is in the class of nonsteroidal drugs. The name Aspirin was first used by the German compa
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