Home » Nonfiction » Romas Baronas » Mathematical Modeling of Biosensors

May 19 , 2009

Mathematical Modeling of Biosensors

An Introduction for Chemists and Mathematicians


Biosensors are analytical devices in which speci?c recognition of the chemical substances is performed by biological material. The biological material that serves as recognition element is used in combination with a transducer. The transducer transforms concentration of substrate or product to electrical signal that is amp- ?ed and further processed. The biosensors may utilize enzymes, antibodies, nucleic acids, organelles, plant and animal tissue, whole organism or organs. Biosensors containing biological catalysts (enzymes) are called catalytical biosensors. These type of biosensors are the most abundant, and they found the largest application in medicine, ecology, and environmental monitoring. The action of catalytical biosensors is associated with substrate diffusion into biocatalytical membrane and it conversion to a product. The modeling of bios- sors involves solving the diffusion equations for substrate and product with a term containing a rate of biocatalytical transformation of substrate. The complications of modeling arise due to solving of partially differential equations with non-linear biocatalytical term and with complex boundary and initial conditions. The book starts with the modeling biosensors by analytical solution of partial differential equations. Historically this method was used to describe fundamental features of biosensors action though it is limited by substrate concentration, and is applicable for simple biocatalytical processes. Using this method the action of biosensors was analyzed at critical concentrations of substrate and enzyme activity.
Show more...

How to download book

Buy this book

You can buy this book now only for $135.39. This is the lowest price for this book.

Buy book

Download book free

If you want to download this book for free, please register, approve your account and get one book for free.


After that you may download book «Mathematical Modeling of Biosensors»:

Download ePUB 2:


Download ePub:


Download DOCX:


Download MobiPocket: