Home » Biography & Memoir » Alexander Monro » Experiments on the Nervous System with Opium and Metalline Substances

November 09 , 2007

Experiments on the Nervous System with Opium and Metalline Substances

Made Chiefly with the view of Determining the Nature and effects of Animal Electricity


Example in this ebook

Download fb2

Read also

Strange Bedfellows

The pervasive influence of law on medical practice and clinical bioethics is often noted with a combination of exasperation and lamentation. Physicians and non-physician bioethicists, generally speaking, consider the willingness of courts, legislatures, and regulatory agencies to insinuate themselves into clinical practice and medical research to…

When, in November last, I began to make Experiments on Animal Electricity, of which I read some account to the Royal Society on the 3d of December; I was not only much hurried with business, but could not procure a sufficient number of Frogs for the purpose. During the last winter and spring, I prosecuted the subject more fully and with greater attention; and, on the third day of June, I read a second paper to the Royal Society, to which I have, since that time, made additions. I shall now state a summary of the chief circumstances I have observed, with a few Remarks.



As my Experiments with Opium, as well as those on Animal Electricity, have been performed on Frogs chiefly; I shall premise some observations on their Circulating and Nervous Systems.
Their Heart consists of one Auricle and one Ventricle only, their Aorta supplying their Air Vesicles or Lungs, as well as all their other Organs; and, of course, their Venæ Cavæ return the Blood from all parts to the Heart. The Ventricle of their Heart contracts about sixty times in a minute; and the purple colour of the Blood which is seen within it, disappears after each contraction, or the Blood is entirely expelled by its contraction. For upwards of an hour after cutting out its Heart, a Frog can crawl or jump; and, for upwards of half an hour longer, it contracts its Legs when the Toes are hurt, though not with sufficient force to more its Body from the place where it is laid.
Their Encephalon consists of Brain and Cerebellum, each of which, on its upper part, is divided into two Hemispheres; and, below, they are conjoined by thick Crura, which form the Medulla Oblongata and Spinal Marrow, both of which are proportionally larger than in Man, and more evidently consist of two Cords. There are nine true Vertebræ; and at the sixth of these, the Spinal Marrow terminates in the Cauda Equina. The Sciatic Nerves are formed by three pairs of Nerves, sent out below the seventh, eighth and ninth Vertebræ, and by one pair from the Os Sacrum. A Nerve, resembling our great Sympathetic Nerve, passes downwards from the Abdomen into the Pelvis.
Two days after cutting off the Head of a Frog at its joining with the first Vertebra, I found it sitting with its Legs drawn up, in their usual posture; and when its Toes were hurt, it jumped with very considerable force. Its Heart likewise continued to beat about forty times in a minute, and so strongly as to empty itself and circulate the Blood.
In several Frogs, after cutting off the back part of the six undermost true Vertebræ, I took out all that part of the Spinal Marrow with the Cauda Equina which they cover. The lower Extremities were rendered insensible to common injuries, and lay motionless, yet the Frogs lived several months thereafter, and the wounded parts of their Backs cicatrised; and the Bones of their Legs, which I fractured, were re-united, the Blood circulating freely in their Vessels.
It is universally known, that if, after amputating the Limb of a warm blooded Animal, we repeatedly irritate the Nerves which terminate in Muscles, repeated Convulsions of the Muscles are for some time produced; and that in Frogs, and other cold blooded Animals, the Nerves retain this power still longer.
But it has been commonly supposed, that, after irritating the Nerve a given number of times, the effect ceases, Authors conceiving that there is lodged in the Nerve some fluid, or other energy which is exhausted by repeated explosions. Instead of this, I have found that the time the Nerves preserve their power is the same, whether we irritate them or not; or that their energy is not exhausted by irritation, unless the irritation be such as sensibly alters their texture.

To be continue in this ebook

Show more...

How to download book

Buy this book

You can buy this book now only for $1.99. This is the lowest price for this book.

Buy book

Download book free

If you want to download this book for free, please register, approve your account and get one book for free.


After that you may download book «Experiments on the Nervous System with Opium and Metalline Substances»:

Download MobiPocket:


Download Torrent: