These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of the book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles.
1. Palladium chemistry of heterocycles has its "idiosyncrasies stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles.
2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containing natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups.Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field.We also hope this book will spur more interest and inspire ideas in such an extremely useful area.
This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle.The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles.
Many heterocycle-containing natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups.Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field.It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting area.
Read alsoTrouble Travels in Threes
[Siren Menage Everlasting: Erotic Menage a Trois Romance, M/F/M, spanking, HEA] The McCalls are taken to their knees when Markie is abducted and taken to an undisclosed location. The perpetrator terrorizes Trouble's founding fathers by sending various photographs showcasing the progressive stages of his captivity. Unaware of Markie's abduction,…
- Includes 3 new chapters
- Incorporates material from selected well-respected authors on heterocyclic chemistry